Certified Nurses Operating Room (CNOR) Practice Exam

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Which inhalation anesthetics are known to cause less postoperative nausea and vomiting (PONV)?

  1. Halohexane and Chloroform

  2. Sevoflurane and Desflurane

  3. Isoflurane and Nitrous oxide

  4. Enflurane and Halothane

The correct answer is: Sevoflurane and Desflurane

Sevoflurane and Desflurane are well recognized for their favorable profile when it comes to postoperative nausea and vomiting (PONV). Both of these agents are newer inhalational anesthetics that tend to be less emetogenic—meaning they provoke less nausea and vomiting compared to some older inhaled agents. Sevoflurane, in particular, is often preferred for its smooth induction and emergence, along with its relatively low incidence of side effects such as PONV. Desflurane, while potentially causing respiratory irritation at high concentrations, also exhibits lower rates of PONV due to its rapid elimination from the body, allowing patients to wake up more quickly and potentially reduce the risk of experiencing postoperative nausea. In contrast, the other options list older inhalation anesthetics that have been associated with higher incidences of nausea and vomiting following surgery. Therefore, the identification of Sevoflurane and Desflurane as the correct answer stands on their better outcomes related to PONV.